Grip tightens on virus outbreaks

Grip tightens on virus outbreaks

between people. Because production in hens’ eggs is slow, six months’ work would be required to manufacture two shots for everybody. UK expert John Oxford argued that, instead of waiting for the crucial genetic shift, the UK government should order H5N1 vaccine for the entire population now. It was, he said, better to have something than nothing. Immunisation with the existing product would “ha...

Tangled DNA tightens chromosomes

Tangled DNA tightens chromosomes C ramming your vacation wardrobe into your luggage is a breeze compared with the packing job cells perform. Before they can divide, they have to scrunch long DNA molecules into tiny chromosomes. The tangles that form in DNA molecules help this chromosome compression, Kawamura et al. report. The team studies newt chromosomes—they are large and convenient to obser...

PCNA tightens its hold on the nucleus

The sliding clamp protein PCNA is a key controller of multiple processes in DNA and chromatin metabolism, regulating replication, repair and chromatin assembly through interaction with a huge number of partner proteins (Fig 1). In many of these transactions, the partners bind via a conserved PCNA-interacting peptide or PIP, first identified in CDKN1/p21. Sequential and competitive binding of th...

Federal government tightens live-in caregiver regulations.

moved to protect foreign workers who’ve been brought to Canada to be live-in caregivers by imposing tighter restrictions on employers. The changes will include the creation of a public “blacklist” that will articulate the names of employers who fail to comply with minimum standards for working conditions. The blacklist will be posted on Citizenship and Immigration Canada’s website. As well, emp...

Grip on Challenging Behaviour